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KMID : 0356620020170020292
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Journal of Korean Society of Endocrinology
2002 Volume.17 No. 2 p.292 ~ p.296
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A Case of Functioning Paraganglioma in Posterior Mediastinum
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Choi Chang-Hoon
Park Si-Hyung
Lee Soon-Hee
Kim Jung-Guk
Ha Sung-Woo
Kim Bo-Wan
Lee Sang-Chul
Lee Eung-Bae
Park Tae-In
Lee Sin-Won
Jung Gui-Hwa
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Abstract
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Paraganglioma is an extraadrenal pheochromocytoma originating from chromaffin cells distributed in the sympathetic nervous systems. Functioning extraadrenal paragangliomas represent more than 10% of all pheochromocytomas, and seems to be highly malignant tumor in comparison to intraadrenal pheochromocytomas. Recently, we experienced a case of a paraganglioma in the posterior mediastinum. A 32-year-old woman was admitted to hospital due to dyspnea on exertion, and intractable hypertension. A chest X-ray showed a well-defined mass density on the right cardiac border, and biochemical studies showed characteristic findings of pheochromocytoma. A solitary pheochromocytoma was located in the posterior mediastinum using 131I-MIBG scintigraphy. The clinical manifestations, including hypertension and dyspnea were improved after operation.
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KEYWORD
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Paraganglioma, Posterior mediastinum, Hypertension
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